| abstract |
Aqueous aerosol preparation for the inhalation application of biologically active macromolecules as an active substance, the aqueous aerosol preparation being characterized in that it contains highly concentrated biologically active macromolecules and the active substance in a concentration between 3 mg / ml and 150 mg / ml, preferably between 25 and 100 mg / ml, of the following compounds selected from the following group: Antisense oligonucleotides Ovexins Erythropoietin Tumor necrosis factor-alpha Tumor necrosis factor-beta G-CSF ("Granulocyte colony stimulating factor", from "granulocyte colony stimulating factor"). GM-CSF ("Granulocyte-macrophage colony stimulating factor" granulocyte-macrophage colony stimulating factor "). Annexins Calcitonin Leptins Parathyroid hormones fragments of parathyroid hormones Interleukins such as e.g. ex. interleukin 2, interleukin 10 and interleukin 12 ICAM ("intercellular adhesion molecule", from "intercellular adhesion molecule") soluble Somatostatin Somatotropin tPA ("Tissue plasminogen activator", from "tissue plasminogen activator"). ... |