http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-4950608-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2b9dc89cc4ba060cc73bbf0c90bbb78 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate | 1998-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5fba3eb220812d166eac85fd0a738a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_123e73e40f33cd0f4b9dbb3faea3fa9d |
| publicationDate | 2000-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CO-4950608-A1 |
| titleOfInvention | NEW DERIVATIVES OF PIPERAZINE AND PROCESSES FOR ITS PREPARATION |
| abstract | A compound of formula (I) or a salt thereof in which Ra is a group of formula (i) in which P1 is phenyl, bicyclic aryl, a 5- to 7-membered heterocyclic ring containing 1 to 3 selected heteroatoms between oxygen, nitrogen and sulfur, or a bicyclic heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur; R1 is hydrogen, halogen, C1-6 alkyl, C3-6 cycloalkyl, CO-C1-6 alkyl, alkoxy C1-6, hydroxy, hydroxy-C1-6 alkyl, hydroxy-C1-6 alkoxy, C1-6 alkoxy-C1-6 alkoxy, C1-6 alkanoyl, nitro, trifluoromethyl, cyano, SR9, SOR9, SO2 R9, SO2 NR10 R11, CO2 R10, CONR10 R11, CO2 NR10 R11, CONR10 (CH2) to CO2 R11, (CH2) to NR10 R11, (CH2) to CONR10 R11, (CH2) to NR10 CONR11, (CH2) 2 CO2-C1-alkyl 6, CO2 (CH2) to OR10, NR10 R11, NR10 CO2 R11, NR10 CONR10 R11, CR10 = NOR11, NR10 COOR11, CNR10 = NOR11, where R10 and R11 are independently hydrogen or C1-6 alkyl and C is 1 to 4, R2 is hydrogen, has logen, C1-6 alkyl, C3-6 cycloalkyl, C3-6 cycloalkenyl, C1-6 alkoxy, C1-6 alkanoyl, aryl, acyloxy, hydroxy, nitro, trifluoromethyl, cyano, CO2 R10, CONR10 R11, NR10 R11, where R10 and R11 are as defined for R1: a is 1, 2 or 3; - 2 -o Ra is a group of formula (ii) in which P2 and P3 are independently phenyl, bicyclic aryl, a 5- to 7-membered heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur, or a bicyclic heterocyclic group containing 1 to 3 heteroatoms selected from oxygen, nitrogen or sulfur; A is a bond or oxygen, S (O) m where m is 0 to 2, carbonyl, CH2, -CH2 CH2 -, or NR4 where R4 is hydrogen or C1-6 alkyl; R1 is as defined above for formula (I) or R1 is a 5-7 membered heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen or sulfur, optionally substituted with C1-6 alkyl, halogen or C1- alkanoyl 6. R2 and R3 are independently hydrogen, halogen, C1-6 alkyl, C3-6 cycloalkyl, C3-6 cycloalkenyl, C1-6 alkoxy, C1-6 alkanoyl, aryl, acyloxy, hydroxy, nitro, trifluoromethyl, cyano, CO2 R10, CONR10 R11, NR10 R11, where R10 and R11 are as defined for R1; y and b are independently, 1, 2 or 3; Y is -NH-, -NR5 - where R5 is C1-6 alkyl, or Y is -CH2 - or -O-; V is oxygen or sulfur; D is nitrogen, carbon or a CH group; W is (CR16 R17) t where t is 2, 3 or 4 and R16 and R17 are independently hydrogen or C1-6 alkyl, or W is (CR16 R17) or AND # 8209; J where u is 0, 1, 2 or 3 and J is oxygen, sulfur, CR16 = CR17, CR16 = N, = CR16 O, = CR16 S or = CR16 -N17; X is nitrogen or carbon; Rb is hydrogen, halogen, hydroxy, C1-6 alkyl, trifluoromethyl, C1-6 alkoxy, C2-6 alkenyl, C3-7 cycloalkyl, optionally substituted with C1-4alkyl, or aryl: Ra is hydrogen or C1-6alkyl; and --- is a single bond when X is nitrogen or a single or double bond when X is carbon. |
| priorityDate | 1997-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.