abstract |
Compound of formula Therefore, the present invention refers to compounds of formula: in which: R1 represents a (C2-C6) alkyl; a group - (CH2) n-G where n varies from 0 to 5 and G represents a C3-C13 non-aromatic mono- or polycyclic hydrogen group, optionally substituted by one or more (C1-C3) alkyl; a phenyl (C1-C3) alkyl in which the phenyl group is optionally substituted once or several times by a halogen, by a (C1-C3) alkyl by a (C1-C3) alkoxy; a group - (CH2) nNR2R3 in which n represents an integer from 1 to 6 and identical and different R2 and R3 represent a (C1-C3) alkyl or constitute with the nitrogen atom to which a morpholino group, piperidino are attached , pyrrolidinyl or piperazinyl; X1, X2, X3 or X4 each independently represent a hydrogen, halogen atom, a (C1-C6) alkyl, a (C1-C3) alkoxy or a trifluoromethyl; it is understood that a single one among X1, X2, X3 or X4 possibly represent a hydrogen atom, R4 represents hydrogen, a group - (CH2) nCOOR5 in which n is as defined hereinbefore and R5 represents a hydrogen atom, a (C1-C6) alkyl or a (C6-C10) aryl- (C1-C6) alkyl; a (C1-C6) alkyl; a group - (CH2) nOR5 or a group (CH2) nNR2R3 in which n, R2, R3 and R5 are as previously defined; a group - (CH2) n-tetrazolyl in which n is as defined above, or R4 represents one of those groups in the form of an alkali metal or alkaline earth metal salt; Y1, Y2 and Y3 independently represent a hydrogen, a halogen, a (C1-C3) alkyl; a (C1-C3) alkoxy, a nitro, a cyano, (C1-C6) acylamino, carbamoyl, trifluoromethyl, a COOR6 group in which R6 represents hydrogen, or (C1-C3) alkyl; or one of its salts or solvates. |