| abstract |
Substituted pyridines having the formula (1A), in which A represents aryl with 6 to 10 carbon atoms, which is optionally substituted up to 3 times identically or differently with halogen, hydroxy, trifluoromethyl, trifluoromethoxy, or alkyl, acyl or straight or branched chain alkoxy with up to 7 carbon atoms each, or with a group having the formula NR1 R2, where R1 and R2 are identical or different and represent hydrogen, phenyl, or straight or branched chain alkyl with up to 6 carbon atoms, D represents straight or branched chain alkyl with up to 8 carbon atoms that is substituted with hydroxy, E and L are identical or different and represent straight or branched chain alkyl with up to 8 carbon atoms, which is optionally substituted with cycloalkyl with 3 to 8 carbon atoms, or represent cycloalkyl with 3 to 8 carbon atoms, E has the previously indicated meaning and L represents in this case aryl with 6 to 10 carbon atoms, which is optionally substituted up to 3 times identically or differently with halogen, hydroxy, trifluoromethyl, trifluoromethoxy, or with straight-chain or branched alkyl, acyl or alkoxy with up to 7 carbon atoms each, or with a group having the formula NR3 R4 - 2 -where R3 and R4 are identical or different and have the meaning indicated above for R1 and R2, or E represents straight or branched chain alkyl with up to 8 carbon atoms, or represents aryl with 6 to 10 atoms carbon, which is optionally substituted up to 3 times identically or differently with halogen, hydroxy, trifluoromethyl, trifluoromethoxy, or with straight-chain or branched alkyl, acyl or alkoxy with up to 7 carbon atoms each, or with a group that has the formula NR5 R6 where R5 and R6 are identical or different and have the meaning indicated above for R1 and R2, and L represents in this case straight or branched chain alkoxy with up to 8 carbon atoms or cycloalkyloxy with 3 to 8 carbon atoms, T represents a radical having the formula where R7 and R8 are identical or different and represent cycloalkyl with 3 to 8 carbon atoms or aryl with 6 to 10 carbon atoms, or represent an aromatic, optionally benzo-condensed, 5- to 7-membered heterocyclic compound with up to 3 heterocyclic atoms of the S, N and / or O series, which are optionally substituted up to 3 times identically or differently with trifluoromethyl, trifluoromethoxy , halogen, hydroxy, carboxyl, with straight-chain or branched alkyl, acyl, alkoxy or alkoxycarbonyl with up to 6 carbon atoms each, or with phenyl, phenoxy or thiophenyl which in turn can be substituted with halogen, trifluoromethyl or trifluoromethoxy, and / or the rings are substituted with a group having the formula -NR11 and R12 R11 and R12 are identical or different and have the meaning indicated above for R1 and R2, X represents an alkyl chain or a straight or branched alkyl chain with 2 to 10 carbon atoms each that are optionally substituted up to 2 times with hydroxy, R9 represents hydrogen, and R10 represents hydrogen, halogen, azido, tifluoromethyl, hydroxy, mercapto, trifluoromethoxy, alkoxy straight-chain or branched with up to 5 carbon atoms or a radical having the formula -NR13 R14, where R13 and R14 are identical or different and have the meaning indicated above for R1 and R2, oR9 and R10 together form a carbonyl group with the carbon atom and its salts. |