| abstract |
Cycloalkane-pyridines of the general formula (I), in which A represents aryl with 6 to 10 carbon atoms, optionally substituted by up to 5 times the same or different with halogen, nitro, hydroxy, trifluoromethyl, trifluoromethoxy, or with straight-chain or branched-chain alkyl, acyl, hydroxyalkyl or alkoxy, in each case with up to 7 carbon atoms, or with a group of the general formula -NR3 R4, in which R3 and R4 are the same or different and signify hydrogen, phenyl or straight or branched chain alkyl with up to 6 carbon atoms, D represents an aryl with 6 to 10 carbon atoms, which is optionally substituted by phenyl, nitro, halogen, trifluoromethyl or trifluoromethoxy, or represents a residue of the formula: where R5, R6 and R9 signify cycloalkyls independent of each other with 3 to 6 carbon atoms, or signify aryl with 6 to 10 carbon atoms or signify a 5-7 membered mono-, bi- or tricyclic heterocycle , given the case benzocon dense, saturated or unsaturated, with up to 4 heteroatoms of the S, N and / or O series, the cycles being substituted, in the case of the rings that also contain nitrogen in the N function, optionally up to 5 times in the same way or distinct with halogen, trifluoromethyl, nitro, hydroxy, cyano, carboxyl, trifluoromethoxy, acyl, alkyl, alkylthio, alkylalkoxy, alkoxy or alkoxycarbonyl of each chain with up to 6 carbon atoms, with aryl or aryl substituted with trifluoromethyl with in each case 6 to 10 carbon atoms or with an aromatic heterocycle, optionally benzo-condensed from 5 to 7 members, with up to 3 heteroatoms of the S, N and / or O series, ... |