| abstract |
A compound of formula (I) or a salt or solvate thereof; characterized in that X is N or CH; Y is CR1 and V is N; or Y is N and V is CR1; or Y is CR1 and V is CR2; or Y is CR2 and V is CR1; R1 represents a group CH3 SO2 CH2 CH2 NHCH2 -Ar-, where Ar is selected from phenyl, furan, thiophene, pyrrole and thiazole, each of which could optionally be substituted by one or two halo, C1-4alkyl or C1-4alkoxy groups: R2 is selected from the group consisting of hydrogen, halo, hydroxy, C1-4alkyl, C1-4alkoxy, C1-4alkylamino and di [C1-4alkyl] amino; U represents a phenyl, pyridyl, 3H-imidazolinyl, indolyl, isoindolyl, indolinyl, isoindolinyl, 1H-indazolyl, 2,3-dihydro-1H-indazolyl, 1H-benzimidazolyl, 2,3-dihydro-1H-benzimidazolyl or 1H- group. benzotriazolyl, substituted by a group R3 and optionally substituted by at least one group R4 independently selected; R3 is selected from a group comprising benzyl, halo-, dihalo- and trihalobenzyl, benzoyl, pyridylmethyl, pi ridilmethoxy, phenoxy, benzyloxy, halo-, dihalo- and trihalobenzyloxy and benzenesulfonyl, or R3 represents trihalomethylbenzyl or trihalomethylbenzyloxy, or R3 represents a group of formula wherein each R5 is independently selected from halogen, C1-4 alkyl and C1-4 alkoxy; and n is 0 to 3, each R4 is independently hydroxy, halogen, C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C1-4alkoxy, amino, C1-4alkylamino, di [C1-4alkyl] amino , C1-4alkythio, C1-4alkylsulfinyl, C1-4alkylsulfonyl, C1-4alkylcarbonyl, carboxy, carbamoyl, C1-4alkoxycarbonyl, C1-4alkanoylamino, N- (C1-4alkyl) carbamoyl, NN-di (alkyl C1-4) carbamoyl, cyano, nitro and trifluoromethyl; ... |