| abstract |
The present description provides a liquid formulation suitable for a group B adenovirus, comprising: a) a group B adenovirus, such as replication competent group B adenovirus, b) 15 to 25% v / v glycerol, for Example 16, 17, 18, 19, 20, 21% v / v of glycerol; and c) 0.1 to 1.5% v / v of ethanol, for example 0.2-1%, such as 1% v / v of ethanol; and d) a buffer, and e) optionally an amino acid, wherein the pH of the formulation is in the range of 8.0 to 9.6, and use thereof in the treatment, in particular in the treatment of cancer. |