abstract |
The present invention relates to a pharmaceutical complex formulation that includes amlodipine, losartan and chlorthalidone as active ingredients. The pharmaceutical complex formulation of the present invention that includes amlodipine, losartan and chlorthalidone as active ingredients has excellent dissolution characteristics of the active ingredients, and has a high uniformity of content and thermal stability. Therefore, the complex formulation of the present invention can be used as a prophylactic or therapeutic agent for cardiovascular diseases, which has excellent quality and thermal stability. |