| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_968c7a35f4d590e7dc4262f1892bf2c5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6939
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1641 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
| filingDate |
2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84e906aab49c716a8c0ffe5d33ffded8 |
| publicationDate |
2018-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CO-2017012573-A2 |
| titleOfInvention |
Formation of cyclosporine a / cyclodextrin nanoparticles |
| abstract |
Methods of formation of nanoparticles and microparticles of cyclosporine / cyclodextrin complex, and administration of the nano- and micro-suspension formed for an eye of a human or animal in the form of aqueous eye drops suitable for causing or improving the formation of tears and for the treatment of diseases of the eye and the surrounding areas. The aqueous eye drop composition contains cyclosporine and a mixture of α-cyclodextrin and γ-cyclodextrin as well as one or more stabilizing polymers. Α-Cyclodextrin solubilizes cyclosporine while γ-cyclodextrin promotes the formation of aggregates of the cyclosporine / cyclodextrin complex. The polymers stabilize the nano- and aqueous micro-suspension. |
| priorityDate |
2015-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |