| abstract |
Substituted benzoxaborols are provided whose structure comprises formula III, where R3 is selected from –CH3, –CH2CH3, –CH2 = CH2, –CH2CH2CH3, –CH (CH3) 2, –CH2CH2 = CH2 and cyclopropyl, R1 and R2 are each independently selected from H, -CH3, -CH2CH3, -CH2CH2CH3 and -CH (CH3) 2; compositions containing these compounds, their use in therapy, including their use as anti-mycobacterial agents, for example, in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of these compounds. |