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filingDate 2017-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CO-2017005014-A2
titleOfInvention 4-phenylthiazole-2-carboxamide and 4- (pyridin-3-yl) thiazole-2-carboxamide modulators of the nuclear receptor rorγt
abstract The present invention comprises compounds of Formula I. Formula I where: X, A1, A2, A3, A4, R1, R2 and R3 are defined in the specification. The invention further comprises a method of treating or ameliorating a syndrome, disorder, or disease, wherein the syndrome, disorder, or disease is rheumatoid arthritis or psoriasis. The invention further comprises a method of modulating RORγt activity in a mammal by administering a therapeutically effective amount of at least one compound according to claim 1.
priorityDate 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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