| abstract |
4,6-Dibromo-3-Hydroxypicolinitro can be prepared from furfural in a series of selected chemical steps of cyano-amination, amine salt formation, and bromination-rearrangement. 4-alkoxy-3-hydroxypicolinilic acids can conveniently be prepared from 4,6-dibromo-3-hydroxypicolinonitrile in a series of selected chemical steps of bromine substitution, nitrile hydrolysis, and halogen reduction. The present invention relates to the reagents and intermediates used in the synthesis of 4,6-dibromo-3-hydroxypicolinitrile and 4-alkoxy-3-hydroxypicolinilic acids. |