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filingDate 2021-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca207b6e0bd726a77159328c6f39699d
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publicationDate 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-216456090-U
titleOfInvention A nano-drug carrier with tumor cell membrane targeting based on light-triggered reactive oxygen species
abstract The utility model discloses a nano-drug carrier with tumor cell membrane targeting based on light-triggered reactive oxygen species sensitivity, which comprises a drug-carrying inner core layer, and the drug-carrying inner core layer is interwoven by polymer polymer drug-carrying micelles with reactive oxygen species sensitivity. Thus, a target recognition layer, a negative charge layer and a protective layer are sequentially arranged outside the drug-loaded inner core layer. The utility model can improve the solubility of the drug, greatly prolong the action time of the drug, greatly increase the tumor distribution of the drug, and simultaneously trigger the active oxygen Realize the targeted and controlled release of drugs in tumor cell membranes, improve bioavailability, realize photodynamic conversion effect, and improve system biosafety. At the same time, it can also guide anti-tumor by tracking the dynamic position of nanoparticles in in vitro cells or in vivo tissues treatment process.
priorityDate 2021-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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