Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66e061087b8b0ca4bda35df8e395be73 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-627 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2005-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4183c132e6ec5d6d9d30cb5ee1a5d486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26d2689b0c0e11ae4b92eeca598b9c16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dadc2f578f3dc0f1406a0a251dc95f10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ef85ac190256468742b88afb9af7f7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddcd6538ddfbe67b385ab8524e58f20f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cca02d05bf794e87584c7f47108e31e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b9e7ec6225f82bde045b3b7bef0cb40 |
publicationDate |
2013-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-1984679-B |
titleOfInvention |
Methods for preparing immunogenic conjugates |
abstract |
The invention discloses methods for making an immunogenic conjugate that includes a hapten or an antigen covalently linked to a carrier. The methods include reacting a first agent with a dihydrazide resulting in a hydrazino-modified first agent, wherein the first agent is a hapten, an antigen or a carrier; reacting a second agent with a benzaldehyde compound resulting in a benzaldehyde-modified second agent, wherein the second agent is a hapten, an antigen or a carrier, provided that the first agent or the second agent is a carrier; and reacting the hydrazine-modified first agent with the benzaldehyde-modified second agent resulting in an immunogenic conjugate comprising a hapten or an antigen covalently linked to a carrier via a hydrazone linkage. |
priorityDate |
2004-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |