| abstract |
The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) wherein R<1>, R<2>, R<3> and X are as defined in the claims, and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and methods of treatment comprising administration of said compounds to a mammal. |