| abstract |
The invention relates to a compound of a general formula (I), wherein: A=N or CR2; R2=H, F, OH, CN, CF3, C1-6 alkyl, C1-6 alcoxy; n=2 or 3 and m=2 when A=N; n=1, 2 or 3 and m=1 or 2 when A=CR2; B=ovalent bond or C1-8 alkylene; R1=optionally substituted heteroaryl; R3=CHR4CONHR5; R4=H or C1-6 alkyl; R5=H, C1-6 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-Cl-6 alkylene; a base, an acid addition salt, a hydrate a solvate thereof. The invention also relates to the application thereof in therapeutics. |