abstract |
A target polypeptide for screening drugs for the treatment and/or prevention of cancer, which is a polypeptide with a length of ≤200 amino acids, and comprises a nuclear localization signal domain having about 70% to 100% identity with the mammalian MYC protein amino acid sequence. A fusion protein comprising the target polypeptide, an isolated polynucleotide encoding the target polypeptide, and a method for screening drugs for treating and/or preventing cancer with the target polypeptide or the fusion protein. |