http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115247193-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f452848d83a02b9411981751173fcb96 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-04005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-385 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-78 |
| filingDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e1f9d7abe61244790a32d4e6122c6ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_371705fcd850455f30a5f8496143773d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65b2787448cd8a56c324b864075f6983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd155cf1b687ecd1eb902ca3f23cbf0a |
| publicationDate | 2022-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115247193-A |
| titleOfInvention | A kind of industrialized production method of uridine |
| abstract | The invention belongs to the field of biotechnology, and in particular relates to an industrialized production method of uridine. The production method adopts a feed liquid containing cytidine or a crude cytidine product as a substrate configuration solution, which flows through an immobilized cytidine deaminase resin column, the transformation temperature is 25-35 ° C, the pH: 7-9, and the transformation time is 6 ‑8h. The conversion solution was detected by HPLC, when the conversion rate was greater than 98%, the conversion was stopped and the conversion solution was collected. The transformation solution is decolorized, concentrated, crystallized, dried, and refined to obtain the finished product of uridine. After actual production, the conversion rate is over 98%, the HPLC purity of the finished uridine is over 99.8%, and the cumulative yield of multiple batches is over 86%. The immobilized enzyme resin column can continuously transform more than 10 batches, and the transformation efficiency does not decrease significantly. After the efficiency of the resin column is reduced after multiple conversions, the enzyme is re-column and the resin can be reused. The method utilizes relatively low-value cytidine raw materials to obtain high-value uridine products, has high production efficiency, low production cost, and is favorable for industrialized continuous production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114990176-A |
| priorityDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.