| abstract |
The invention belongs to the technical field of biomedicine and discloses a black-spotted frog-derived antimicrobial peptide Brevinin-1EG and an application thereof. The black-spotted frog-derived antimicrobial peptide Brevinin-1EG is a polypeptide encoded by the black-spotted frog, and the black-spotted frog source The precursor amino acid sequence of the antimicrobial peptide Brevinin-1EG is SEQID NO.2; the molecular weight of the black-spotted frog-derived antimicrobial peptide Brevinin-1EG is 2637.28 Daltons, the isoelectric point is 9.50, and the average hydrophilic coefficient is 0.815, so the The amino acid sequence of the black-spotted frog-derived antimicrobial peptide Brevinin-1EG is SEQ ID NO.3. The antibacterial peptide Brevinin-1EG of the present invention has the characteristics of small molecular weight, simple synthesis, efficient antibacterial activity, no obvious side effects, etc., and can be used as a new type of antibacterial product or drug, and can be used in the fields of medicine, food, breeding and the like. |