http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115236344-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d6853f9a10534e4e69c08db83541011 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2001-2893 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-28 |
| filingDate | 2022-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c0e225a42a83c750da4e2a2f94e0c0e |
| publicationDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115236344-A |
| titleOfInvention | Glycated hemoglobin calibrator and preparation method and application thereof |
| abstract | The invention relates to the field of biomedicine, in particular to a glycosylated hemoglobin calibrator and a preparation method and application thereof. The present invention has a protective effect on in vitro glycosylated hemoglobin, overcomes the defects of easy oxidation and glycosylation of glycosylated hemoglobin, and the glucose oxidase provided by the present invention can rapidly react with glucose that has not reacted with hemoglobin before to generate δ-gluconic acid Esters, δ-gluconolactone is self-hydrolyzed into gluconic acid in a non-enzymatic reaction, after which the available glucose of hemoglobin is very small, thereby ensuring that the concentration of calibrator glycosylated hemoglobin will not increase; the present invention uses tagatose as an excipient , it will not stab the protein during the freeze-drying process, and will not be used by microorganisms, so that the glycosylated hemoglobin is in a stable state during the storage process, thereby improving the stability of the calibrator; High stability and good accuracy have good prospects for industrial production and clinical application. |
| priorityDate | 2022-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.