| abstract |
The invention discloses an indolyl conjugated tri-indene derivative fluorescent dye, a preparation method and application thereof, and its chemical structure is shown in (I). 2,3,3-trimethyl-1-propyl-3H-indole salt as raw material, can obtain indolyl trimer indene derivative (I) through Knoevenagel condensation reaction. The preparation method has simple reaction steps, mild reaction conditions, good selectivity and high yield. The compounds have significant solvent effect, good cell permeability and biocompatibility, can be used for cell fluorescence imaging, and have potential applications in the field of molecular biology and medicine. |