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filingDate 2022-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed98a72da568fdae8be2aa4a8d294180
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publicationDate 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-115227832-A
titleOfInvention Application of plant-derived nanoparticles in the preparation of drugs for preventing and treating vascular calcification
abstract The invention belongs to the technical field of biomedicine, and particularly relates to the application of plant-derived nanoparticles in the preparation of medicines for preventing and treating vascular calcification. Experimental studies have confirmed that for the mouse vascular smooth muscle cells induced by high phosphorus and the vascular calcification model of mice induced by high vitamin D3 , the grapefruit-derived nanoparticles provided by the present invention can effectively relieve vascular calcification; and membrane potential did not cause significant changes, nor did it cause damage to the main organs of mice (heart, liver, spleen, lung, kidney), with high stability and good safety, it is expected to be applied to vascular calcification diseases In the prevention and treatment of vascular calcification, it provides a new idea and a better prevention and treatment plan for the treatment of vascular calcification.
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