| abstract |
The invention relates to the field of medicine, in particular to a musk analgesic gel patch and a preparation method thereof. The gel patch is a water-soluble base, and the active ingredients of this product, the raw chuanwu, pepper and red fennel root, are extracted from high-concentration ethanol solution, and the content of fat-soluble components in the concentrated solution is relatively high. . During the test, it was found that the alcohol-extracted active components were mixed with water-soluble ingredients such as belladonna extract, artificial musk extract, methyl salicylate and camphor, and more insoluble precipitation occurred. More clumps and scattered black patches were produced, and the formulation could not be formed. The preparation method of the present invention can ensure a high degree of fusion of the prescription drug and the matrix, the preparation stability is good, the cross-linking and curing can be performed without the process of drying the sheet after forming, and the product can be directly put into the inner bag after coating and slitting. Cross-linked curing. |