Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8e97b6f5b3285b7c1704905e2c42991 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfc27873a8f550e25a0d82ee15cdb1f2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
filingDate |
2021-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aa7f841bfe06e1bb1b37a15393b04e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f33b99aa1dc1788c937e2f5f711ab047 |
publicationDate |
2022-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-115215869-A |
titleOfInvention |
Substituted tricyclic inhibitor and preparation method and application thereof |
abstract |
The present invention relates to a substituted tricyclic inhibitor and its preparation method and application. Specifically, the compound of the present invention has the structure shown in formula (I). The present invention also discloses a preparation method of the compound and its use as an inhibitor of SOS1. The compound of the present invention has a good selective inhibitory effect on SOS1 and has Better pharmacodynamics, pharmacokinetic properties and less toxic side effects. |
priorityDate |
2021-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |