http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115212931-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8840ee580cbe5fb1b6dc0b170fd2024e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0681 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
| filingDate | 2021-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed8901d4052b4fcfbf7855358c4b12bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf7b42cb452d8a0944c3a0a142997bc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abae3d089613e5f7ba29d0c68575b4af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72531de9c41d34cd01dccdd6aa884f45 |
| publicationDate | 2022-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115212931-A |
| titleOfInvention | A kind of platelet in vitro release system and platelet production method |
| abstract | The invention provides an in vitro platelet release system and a platelet preparation method, comprising: a cover body, a cavity part, a raw material inlet, a product outlet and a driving liquid inlet, the cavity part is arranged inside the cover body, the raw material inlet, the product outlet and the driving liquid The liquid inlets are all set on the surface of the cover body; the filter membrane includes a filter membrane body and a number of filter holes arranged on the filter membrane body, the filter holes are tapered, the large mouth of the filter hole faces the upper half of the cavity, and the large mouth of the filter hole The caliber is 6μm～20μm, the diameter of the small mouth is 2μm～6μm, the thickness of the filter membrane body is 10μm～100μm; the pressure regulating device and the flow regulating device. The beneficial effect of the present invention is that: megakaryocytes enter the microfluidic chip and are trapped by the conical micropore array and deformed under the action of pressure, and part of the megakaryocytes are squeezed out of the conical pores, and the megakaryocytes are subjected to shear force and parallel filter membrane shear force and The platelets are released under the turbulent flow created by the microstructure. Mass production of platelets can be achieved by continuous infusion of megakaryocytes. |
| priorityDate | 2021-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.