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filingDate 2022-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14346346eb672e77f254260e348e23f9
publicationDate 2022-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-115212369-A
titleOfInvention A hemoperfusion device for decomposing homocysteine
abstract The present invention provides a hemoperfusion device for decomposing homocysteine, comprising a shell with a built-in modified filler resin particle, and the preparation method of the modified filler resin particle includes the following steps: Step 1, take CMS -Na is evenly dissolved in the isopropanol aqueous solution to obtain solution A; step 2, adding NaOH to solution A to obtain solution B; step 3, pouring sodium chloroacetate into solution B and neutralizing it with HCl solution to neutrality, Obtain HS-CMS-Na; Step 4, add HS-CMS-Na into deionized water, add polystyrene resin particles and sodium hexametaphosphate respectively and shake at room temperature to obtain HS-CMS-Na coated polyphenylene Vinyl resin particles; in step 5, after the PBS buffer, EDC solution, cystathionine β-synthase, and cystathionine γ-lyase are fully mixed, add HS-CMS-Na-coated polystyrene resin particles, namely The modified filler resin particles are obtained, whereby the present invention has the advantage of improving and reducing the content of homocysteine in blood.
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