http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115197689-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68cac1f07608a5e1156d79a75c574956 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-7773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2022-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b18354e6cfaa4deaaa7448b9f4ae89d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c09924425660c194fcbea68a0f2ae6f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b924bee6b97390e1bf5f3396f9cb857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2178a779842a6819146ee4b92a9911ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1839bebdf937a57db4211756f1dd9b9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8bb39c161d895ee371e8c5b554b9581 |
| publicationDate | 2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115197689-A |
| titleOfInvention | A kind of functionalized upconversion nanoparticle of photo-oxidative protein and its preparation method and application |
| abstract | The invention belongs to the technical field of nanomaterials, and in particular relates to a functionalized up-conversion nanoparticle of photo-oxidative protein and a preparation method and application thereof. The preparation method of the functionalized up-conversion nanoparticles of the photooxidized protein of the present invention comprises the following steps: (1) coating the surface of the up-conversion nanoparticles with silicone to obtain the up-conversion nanoparticles coated with silicone; (2) An amino group is attached to the surface of the organosilicon-coated up-conversion nanoparticles to obtain aminated up-conversion nanoparticles; (3) the aminated up-conversion nanoparticles are modified with sulfuryl chloride-modified thioflavin S, That is, the functionalized up-conversion nanoparticles of the photo-oxidative protein are obtained. The functionalized up-conversion nanoparticles of photooxidized proteins prepared by the method of the present invention have near-infrared light absorption ability, and can generate reactive oxygen species for β-amyloid peptide fiber oxidation by near-infrared laser (NIR) irradiation. |
| priorityDate | 2022-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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