| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ccaa712ead346a9763424897c3e27922 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-75 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-75 |
| filingDate |
2022-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c14d503dfa3e090c3cd59cd4d177e9eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64b4b3e9ccd7006270f36d053c5f17bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7360c0b2dd7fc81378dff96f3de980ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_992afd29987e591df9f63651487ccbb1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_129888c2c0dd47bd2a6bb5a0f6d8dd14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca0c08573c66daea5aec24c60a5cd812 |
| publicationDate |
2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-115197315-A |
| titleOfInvention |
Method for preparing human fibrinogen by chromatographic method using cryoprecipitation as raw material |
| abstract |
The present invention provides a method for preparing human fibrinogen by using cryoprecipitation as a raw material by chromatography, comprising the following steps: (1) preparation by crude and pure precipitation; (2) dissolving and filtering; (3) S/D virus sterilization (4) capto q xp gel chromatography; (5) ultrafiltration dialysis; (6) lyophilization and dry heat inactivation. The method for preparing human fibrinogen by using cryoprecipitation as a raw material by chromatography has the advantages of simple process in the preparation process, reducing centrifugation steps in the process, single-step gel adsorption, and effectively improving product purity; it includes two steps of virus The inactivation step can inactivate known lipid-enveloped/non-lipid-enveloped viruses, and the safety of clinical viruses is greatly guaranteed. |
| priorityDate |
2022-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |