| abstract |
The invention relates to a preparation method of a flumatinib intermediate, a synthesis process of an antitumor drug flumatinib intermediate, in particular to a flumatinib intermediate 2-methyl-N3-(4-(pyridine) -3-yl) pyrimidin-2-yl) pyridine-3,5-diamine preparation method. The synthesis method has easy-to-obtain raw materials, simple process, high yield, and is suitable for scale-up production, and is an environment-friendly preparation method for an intermediate of flumatinib. |