Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9104aeeb6512fcbc9f077b57a1ad8503 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate |
2022-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fcc1b74c0fb87da40921382d2771738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_074620a5ad9f37f71a84e04829695bd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ea97d4d352b5f3fb48dfa5de4f778ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e757877534be1ad71caabcc026f6a40d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ce2871efcf2108744af12cf4669c47c |
publicationDate |
2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-115192596-A |
titleOfInvention |
Application and medicine of ginsenoside Rg3 |
abstract |
The invention discloses the application of ginsenoside Rg3 as a microglia hyperactivation inhibitory drug. Ginsenoside Rg3 increases the expression level of FGFR1 protein in microglia by regulating the FGF2/FGFR1 signaling pathway in microglia; at the same time, it inhibits the inflammation of microglia, and finally inhibits the overactivation of microglia, reduces neuronal damage, and has a reversible effect. Effects of prolongation of PTSD-like freezing time and blocking PTSD-induced anxiety-like behaviors in animal models. The invention also discloses a drug for inhibiting the hyperactivation of microglial cells. |
priorityDate |
2022-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |