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filingDate 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99bbe86785a8a756d73f383e5173111b
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publicationDate 2022-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-115184420-A
titleOfInvention A preparation method of hemoglobin biosensor based on carboxyl-functionalized phosphine-based ionic liquid@multi-walled carbon nanotubes
abstract The invention provides a preparation method of a hemoglobin biosensor based on a carboxyl-functionalized phosphine-based ionic liquid@multi-walled carbon nanotube, belonging to the technical field of material preparation and electrochemical biosensing analysis. In the present invention, hydrophobic carboxyl-functionalized phosphine-based ionic liquid is synthesized by hydrothermal method and room temperature stirring method in turn, and ionic liquid@multi-walled carbon nanotube hybrid material is prepared by one-step ultrasonic method, and then it is drop-coated on glassy carbon electrode Then, hemoglobin and Nafion were sequentially drop-coated on the surface of the ionic liquid@multi-walled carbon nanotube-modified electrode to construct a hemoglobin biosensing platform for the detection of the organophosphorus pesticide methyl parathion. The sensor constructed by the invention has the advantages of simple procedure, convenient operation and low cost. The synthesized sensing substrate helps to improve the stability of the electrode interface and the electron conductivity, overcomes the shortcomings of low sensitivity of the traditional electrochemical analysis method, and has the advantages of simple procedure, convenient operation, The cost is low, the electrochemical detection accuracy and detection efficiency are improved, and the detection limit is 0.62 ng/mL, which is suitable for the detection of methyl parathion.
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