Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2b5005b473b73e158899328dd7e6331 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-20 |
filingDate |
2022-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0329f738f339894f52b0696b0010d86f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c82ddc3b29cc246eacdb3d868253ffe |
publicationDate |
2022-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-115181798-A |
titleOfInvention |
Parkinson's disease cognitive impairment marker and construction method and application of disease prediction model based on the marker |
abstract |
The invention discloses a Parkinson's disease cognitive impairment marker and a construction method and application of a disease prediction model based on the marker. The marker includes at least one of IGLC1, IGLV3-21, IGLV1-44, CARD17 and ZFP91-CNTF , which can be used to construct a model to dynamically predict the progression of PD patients to MCI or CI, with high specificity and accurate detection effect. The gene expression level based on the longitudinal change of this marker can dynamically and accurately predict the progression of PD-MCI and classify the PD-MCI risk group. damage, and only need to provide very little variable data to achieve detection. |
priorityDate |
2022-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |