http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115178748-B

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filingDate 2022-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-115178748-B
titleOfInvention A method for improving the stability of monodisperse gold nanoparticles
abstract The invention discloses a method for improving the stability of monodisperse gold nanoparticles, which belongs to the technical field of nanoparticle preparation. The method includes the following two steps: reducing chloroauric acid with sodium citrate to synthesize AuNPs, using 0.1M NaOH aqueous solution to regulate the pH value of the AuNPs obtained above, and adjusting the pH value to 12. The benefits of the present invention are: (1) After the pH value is adjusted, the charge and conformation of citrate are changed, thereby improving the stability of citrate to AuNPs and obtaining stable monodisperse AuNPs; (2) using the present invention The AuNPs obtained by the provided method not only realize the separation and concentration of nanoparticles, directly modify sulfhydryl molecules or ions, and switch from conventional aqueous phases to organic solvents without adding surfactants, but also slow down the coffee ring effect, and No surfactants were introduced that could generate background signals.
priorityDate 2022-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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