abstract |
The invention belongs to the technical field of preparations, in particular to an oxytocin injection and a preparation method, comprising the following components: oxytocin 5000-10000 IU, chlorobutanol 3.5-5 g, an appropriate amount of pH buffer, and water for injection to 1000ml; the pH value is 3.2-3.8, the present invention effectively improves the stability of oxytocin injection, adopts pH buffer to control the pH range of the preparation to be 3.2-3.8, and preferably adopts acetic acid-sodium acetate buffer to solve uterine contractions It is sensitive to pH and degrades during shelf life, resulting in pH changes. |