abstract |
Compositions and methods for their use are disclosed for reducing tumor necrosis factor alpha (TNF-α) and/or vascular endothelial growth factor (VEGF) production in skin cells by topical application comprising an effective amount of prickly pear fruit , prickly pear cactus stem or a combination of both or extracts thereof to skin in need thereof to reduce TNF-alpha or VEGF production in skin cells. |