| abstract |
The present application provides an RNA plasmid delivery system for the treatment of pulmonary fibrosis. The system includes a plasmid carrying an RNA fragment useful in the treatment of pulmonary fibrosis, the plasmid is capable of enriching in the organ tissue of the host, and in the host organ tissue endogenously and spontaneously The composite structure of the RNA fragment, the composite structure can deliver the RNA capable of inhibiting pulmonary fibrosis into the lung, so as to realize the treatment of pulmonary fibrosis. The safety and reliability of the RNA delivery system for the treatment of pulmonary fibrosis provided by the present application have been fully verified, and the drugability is very good, the versatility is strong, and it has excellent economic benefits and application prospects. |