http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115124556-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d33312e4f9ec8fb118d3fd1d8dbc14a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F3-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F3-00 |
| filingDate | 2021-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88a126e0a5e4c6c01d17228ecd3bec21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d05456108e32b62749613335ca799f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd86445ead4dd3514d52168ca786dc20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_723813e5f26a385c46b086fea13219ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_251169edc49e0387539bd62821794fb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_424a6dd06f8687e9fd7f1426a3f1382e |
| publicationDate | 2022-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115124556-A |
| titleOfInvention | Quenching method for runaway reaction of Grignard reagent preparation and method for preparing Grignard reagent |
| abstract | The invention relates to the field of organic synthesis, in particular to a quenching method for a runaway reaction in the preparation of Grignard reagents. The method comprises: adding a quenching agent to a reaction material for preparing the Grignard reagent; wherein, the quenching agent is selected from the group consisting of formula Compounds shown in (1): Wherein, R 1 and R 2 are each independently selected from C 1 -C 6 alkyl, C 1 -C 6 alkenyl and aryl; wherein, the timing of adding the quencher is: the reaction mass The temperature increase rate reaches 0.5-10°C/s. By this method, a quencher can be added when the preparation reaction of the Grignard reagent is out of control, and the preparation reaction of the Grignard reagent can be quickly, mildly, safely and efficiently terminated when the amount of the quencher is small. |
| priorityDate | 2021-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.