http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115124545-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41ff1c30d072cdea55343c4671923b9e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107 |
filingDate | 2022-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba16723826af39adb87ee3daca9a0951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a93fe53391a1079cee41e2bf8da371c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72ca18de136b87762564b4c6864017df |
publicationDate | 2022-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-115124545-A |
titleOfInvention | A kind of synthetic method of gonadotropin-releasing hormone receptor antagonist intermediate |
abstract | The invention relates to a gonadotropin-releasing hormone receptor (GnRH) antagonist intermediate 8-benzyl-3-oxo-1-oxa-8-aza[4,5]decane-4-carboxylic acid A new method for synthesizing ethyl ester belongs to the technical field of synthesis. The specific synthesis method is to add a solvent to the compound represented by the formula (3) to dissolve, then add a base, the compound of the formula (2), and react at a suitable temperature, that is, The product represented by formula (1) can be obtained; the preparation method of the present invention has fewer reaction steps, higher yield than original reports, low cost, simple post-reaction treatment, and high product purity, which can fully meet market demands. |
priorityDate | 2022-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.