http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115120573-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2022-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-115120573-B |
titleOfInvention | High-efficiency anti-tumor nano drug-carrying system containing hydralazine and its preparation method |
abstract | The invention discloses a high-efficiency anti-tumor nano-drug delivery system (H-NPs) containing hydralazine. The drug-loading system uses hydralazine and adriamycin combined by Glycans serve as the hydrophilic shell. The high-efficiency anti-tumor nano-drug delivery system containing hydralazine of the present invention can expand tumor blood vessels and regulate TME, thereby increasing vascular permeability at tumor sites, blood perfusion, improving the enrichment and penetration of nanoparticles in tumors, reducing Tumor hypoxia increases tumor sensitivity to chemotherapy drug doxorubicin and significantly improves its anti-tumor effect. |
priorityDate | 2022-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.