http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115112904-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7007ba2db892cc54b39fa0cebaf4e3c8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-78 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2022-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_666d60b35a65455e13fe13a92173f75a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5b2244ca72692873754f59ce62d3add http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6be5eaf3f51ff769a1e4035cb767e1c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c4ced8888c17e6a25794ffa0b244f9b |
| publicationDate | 2022-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115112904-A |
| titleOfInvention | A method for detecting the integrity of collagen triple helix structure using collagen peptide-encapsulated metal nanoclusters and disulfide nanomaterials |
| abstract | The invention belongs to the technical field of biological detection, and in particular relates to a method for detecting the integrity of the triple helix structure of collagen by wrapping metal nanoclusters and disulfide nanomaterials with collagen peptides. The method includes: 1) obtaining a collagen peptide-coated metal nanocluster; 2) mixing the collagen peptide-coated metal nanocluster with a disulfide solution; 3) mixing the mixture obtained in step 2) with a collagen standard and a collagen sample to be tested, respectively Mixed, respectively test the maximum fluorescence intensity in the range of 360nm-550nm under the excitation wavelength of 340nm, denoted as F mark , F A , and compared with the fluorescence intensity F 0 of the blank system, the integrity of the triple helix structure in the sample = (F A - F 0 )/(F standard- F 0 )*100%. The detection method provided by the invention has the advantages of simple operation, high sensitivity, short detection time and the like; it can be used for the integrity detection of almost all type I collagen triple helix structures on the market, and the detection range is wide. |
| priorityDate | 2022-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.