| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07ca6ce27c3c100572dfe34b821d3e84 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1767
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43595
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21061 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11346d5690327d683e9388ea547ecbbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7292abe638470b3bb6c3afb1434d45fd |
| publicationDate |
2022-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-115109799-A |
| titleOfInvention |
Fusion plasmid of a small molecule peptide and its application in antitumor drugs |
| abstract |
The invention discloses a fusion plasmid of a small molecule peptide and its application in antitumor drugs, and mainly relates to the field of bioengineering. The preparation method is as follows: GFP is digested with restriction endonuclease to obtain a linearized vector; based on the amino acids at positions 593-618 of PCSK9, a target gene fragment is obtained by PCR amplification; a reaction system is prepared with the linearized vector and the amplified product of the target gene, and the The recombination reaction realizes the in vitro circularization of the linearized vector and the target gene fragment and obtains the recombination product; purifies to obtain a high-purity plasmid. The beneficial effect of the present invention is that it can compete with PCSK9 for palmitoylation modification and restore the expression of PTEN. |
| priorityDate |
2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |