Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ffed7236dae6b3dcb78e91786b2fb3b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8e97b6f5b3285b7c1704905e2c42991 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 |
filingDate |
2021-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1ba788636163087bfdee36894da8d83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3887bd7c7bda1d081db0b27f7bfc9ea |
publicationDate |
2022-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-115109078-A |
titleOfInvention |
Pyrimidopyridine inhibitor and preparation method and application thereof |
abstract |
The present invention relates to a pyrimidopyridine inhibitor and its preparation method and application. Specifically, the compound of the present invention has the structure shown in formula (I). The present invention also discloses a preparation method of the compound and its use as a KRAS G12D inhibitor, which has a good selective inhibitory effect on KRAS G12D and has more Good pharmacodynamics, pharmacokinetic properties and less toxic side effects. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023056951-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023151621-A1 |
priorityDate |
2021-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |