| abstract |
The invention relates to the field of biological products, in particular to a vaccine freeze-drying protective agent and a freeze-drying method thereof. The present invention provides a freeze-dried protective agent for a live attenuated Japanese encephalitis vaccine, comprising: lactose, thiourea, sodium glutamate, L-arginine, sorbitol, glycine, human albumin or sodium hyaluronate one or a combination of two or more. The live attenuated Japanese encephalitis vaccine prepared by the invention has stable appearance and good solubility, and can store the live attenuated Japanese encephalitis vaccine at 37°C for 21 days and at 2-8°C for 36 months. |