http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115097019-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_610a491d3badd24d1ea60fda8d02b7e3 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-062 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cd08947078b8723e018e4eda46f369a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbf1bac305d917af27e9ebcd10648e47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91ac65560d56f3ab2c4570b168caf750 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d83892db90d3e8cbb6ad99f03d5ab9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a22ef04097005bbda9db344a1d01f149 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cde1588db96683254338bf908aef910a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2aa62773cd5a360dd16f79c5cf8d296b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c47c919f69d3981c06cc642819bd912e |
publicationDate | 2022-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-115097019-A |
titleOfInvention | A kind of detection method of methotrexate plasma concentration |
abstract | The invention discloses a method for detecting the plasma concentration of methotrexate, comprising the following steps: S1, adding methanol to normal serum without methotrexate, and collecting the supernatant to obtain A liquid; S2, The magnetic molecularly imprinted polymer is added to methanol for vibration activation, and the reactant is obtained by magnetic separation; S3, the A solution obtained in step S1 and the reactant obtained in step S2 are respectively added to multiple groups of different concentrations of methotrexate In the standard solution, obtain multiple groups of mixtures, extract and load samples, magnetically separate, and then add an eluent to shake and remove impurities to obtain multiple groups of processed materials; S4. Add the eluent to the multiple groups of materials obtained in step S3 respectively. , after magnetic separation, the supernatant was collected and filtered, and the filtrates were detected by HPLC-UV method respectively to obtain a standard curve; S5, the methotrexate standard solution was replaced with an actual blood sample, and the actual blood sample was obtained by calculation. Methotrexate concentration in blood samples. |
priorityDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.