http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115093373-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ccc3b6d255daae624f7a7fbb9a9f9801 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 |
| filingDate | 2022-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28438e2ae1a61bd128ca37f4a24670ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9d005cad5a4705cda43b7ff1c6e3046 |
| publicationDate | 2022-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115093373-A |
| titleOfInvention | A 1,5-disubstituted-3-fluoroalkyl-1,2,4-triazole compound and its preparation method and application |
| abstract | The invention discloses a 1,5-disubstituted-3-fluoroalkyl-1,2,4-triazole compound and a preparation method and application thereof, belonging to the technical field of organic compound preparation. In the present invention, the 2-fluoroalkyl-N-substituted acetyl halide hydrazone represented by the formula (I) is mixed with the imidate and the basic compound represented by the formula (II) in an organic solvent to generate [3+ 2] Cyclization reaction, effectively preparing 1,5-disubstituted-3-fluoroalkyl-1,2,4-triazole represented by formula (III). The invention adopts simple and readily available 2-fluoroalkyl-N-substituted acetyl halide hydrazone to synthesize building blocks, avoids the use of explosive fluoroalkyl diazonium compounds, does not need metal catalysts, has simple operation steps and mild reaction conditions , the regioselectivity is good, the yield is high, and the substrate spectrum is wide, and the obtained compound can be widely used in the fields of organic chemistry, material chemistry and medicinal chemistry. |
| priorityDate | 2022-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.