http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115078610-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61c88792ba37ba7ccc97e25128cb7d6c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-009 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7266 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-18 |
filingDate | 2022-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71234090af31b010ad5d7c2f3608b5b4 |
publicationDate | 2022-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-115078610-A |
titleOfInvention | A kind of method for detecting the content of hydrophobic drug in body fluid |
abstract | The invention discloses a method for detecting the content of hydrophobic drugs in body fluids. The method relates to a liquid phase extraction device supported by hydrophobic and lipophilic fibers in a syringe, combined with flow injection mass spectrometry (FIA-MS) for rapid detection of drugs in body fluids. detection. A simple and easy-to-use device for extracting hydrophobic drugs from body fluid samples is constructed by inserting hydrophobic and lipophilic fibers attached with an oily solvent such as n-octanol between the syringe needle and the needle tube. The sample solution is sucked into the syringe through the plunger rod of the syringe, and the hydrophobic drugs can be quickly extracted to the hydrophobic and lipophilic fibers, and then the desorption solvent is sucked for desorption, and the desorbed liquid is analyzed and detected by FIA-MS. The method can rapidly analyze hydrophobic drugs in complex body fluid samples, enhance the ability to resist matrix interference, and improve the detection sensitivity. In addition, the invention expands the extraction technology in the syringe, and is expected to be developed into an automatic pretreatment device to realize fully automatic analysis. |
priorityDate | 2022-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.