| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c07e187a98c04ca487dfa54e35b7e19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af92759c928daeb7f0daabbb0499f059 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4712
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6441 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-1434
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-14 |
| filingDate |
2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d114fc56737d5803ea670f9b334f8c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b536f6a49d92f7ae6fac7ea527f4fa88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9e301aca181298c7d888d81fce7ac43 |
| publicationDate |
2022-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-115078230-A |
| titleOfInvention |
Methods, kits and devices for obtaining information about spinal muscular atrophy |
| abstract |
An object of the present invention is to provide a novel means for acquiring spinal muscular atrophy-related information based on the intracellular distance between an SMN protein located in the nucleus of a nucleated cell and a specified intranuclear protein. The present invention solves the above-mentioned problems by a method for acquiring information related to spinal muscular atrophy, including labeling the SMN protein in a blood subject-derived nucleated cell obtained from a subject with a first fluorescent dye, and acquiring a specified A fluorescence image of a nucleated cell in which nuclear proteins are labeled with a second fluorescent dye, and the first light spot corresponding to the first fluorescent dye and the second light spot corresponding to the second fluorescent dye are obtained in the fluorescence image. For the distance, a value related to the number of nucleated cells whose intracellular distance is less than or equal to the first threshold value is obtained, and the obtained value is used as an indicator of the development of spinal muscular atrophy. |
| priorityDate |
2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |