http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115074301-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0fc2211e23a61ca4b1207e1cdb0a034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ee33b0e3e7398cf6fc957eeee59d510 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-445 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
filingDate | 2022-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd49f0b2998ad4e8bf34c5f8bfd6bed4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4865fdf12685e04f1b757276dd33dc8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b66194f603da3bbcd11d8504f8abc7f6 |
publicationDate | 2022-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-115074301-A |
titleOfInvention | A method for enriching bacterial extracellular vesicles using ε-polylysine |
abstract | The invention relates to the field of biomedicine, in particular to a method for enriching bacterial extracellular vesicles by utilizing ε-polylysine. The present invention proposes for the first time a method for enriching bacterial extracellular vesicles from biological samples by utilizing ε-polylysine. Compared with the classical ultracentrifugation method, the present invention only needs an ordinary high-speed centrifuge, and does not need to use large and expensive centrifugal equipment; compared with methods such as tangential flow filtration and hydrostatic filtration, the present invention does not need to design and manufacture special filtering devices, and is easy to operate; And this method adopts the precipitation method, compared with ultrafiltration and affinity separation methods, it has a unique large-volume sample processing capability; the reagents used in the present invention include ε-polylysine, and the antibodies used in the affinity separation method. Compared with nucleic acid aptamers, the cost is lower, and it has better economic practicability and clinical application prospects. In addition, this method has the potential to precipitate bacterial-derived vesicles from complex samples such as body fluids, which can promote the development of bacterial vesicle detection and application research. |
priorityDate | 2022-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.