| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae04510d999a5dee3acbd0cc622984a1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1008 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 |
| filingDate |
2022-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_995054ab122657641034b35b33c745de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_023818074f9ea03dcba41de4203c0986
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba12d17aefc976a2b4d511a77936f5a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e6b723c99431d85e00c62f340c6eb9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12f2bfc0081e5b1b52c4379ef96d4d91 |
| publicationDate |
2022-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-115068624-A |
| titleOfInvention |
A kind of peptide dendrimer drug loading system and preparation method and application thereof |
| abstract |
The invention relates to the field of medical technology, and provides a peptide dendrimer molecular carrier based on solving the problem of constructing an all-round environment-responsive collaborative nano-drug-carrying system that can simultaneously realize the synergistic treatment of drugs with different chemotherapeutic mechanisms and the synergistic treatment of drugs with different treatment mechanisms. The drug system includes an enzyme-responsive peptide dendrimer-gemcitabine conjugate and doxorubicin, wherein the mass ratio of the enzyme-responsive peptide dendrimer-gemcitabine conjugate and doxorubicin is 10:1-1:10 , which can simultaneously realize the synergistic treatment of drugs with different chemotherapeutic mechanisms and the all-round environment-responsive synergistic nanosystem of drug synergistic treatment with different therapeutic mechanisms, through the precise and synchronous release of synergistic drugs in the lesion area; chemotherapy and immunostimulation therapy. |
| priorityDate |
2022-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |