http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115058344-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20022
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
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filingDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-115058344-B
titleOfInvention Decoy microrobots for removing SARS-CoV-2 and its mutant strains in wastewater, its preparation method and application
abstract The invention discloses a bait microrobot for removing SARS-CoV-2 and its mutant strains in wastewater, a preparation method and application thereof. The bait microrobot includes: algae and cell membrane vesicles wrapped in the algae, and the cell membrane vesicles are prepared from the cell membrane extracted after the S protein receptor of SARS‑CoV‑2 is overexpressed on engineered cells. Applying the technical solution of the present invention, the simple, safe and effective bait micro-robot can actively remove SARS-CoV-2 and its variants in wastewater. In the present invention, without affecting the movement behavior of algae and the targeting function of ACE2, the transgenic cell membrane vesicles with virus entry protein receptor ACE2 are used to camouflage algae to prepare bait microrobots; the obtained ACE2 algae bait microrobots exhibit Excellent motility for efficient "real-time" removal of SARS‑CoV‑2 spike protein and pseudoviruses in various aqueous matrices.
priorityDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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